Guanidine Thiocyanate

ULTRA DIAGNOSTIC GRADE | GT5221 | CAS#: 593-84-0

Intended For Use in Commercial Manufacturing, Diagnostic and Laboratory Applications

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ULTRA DIAGNOSTIC GRADE | GT5221

CAS #: 593-84-0

Molecular Formula:

C2H6N4S

Solubility in Water (g/L): 1,600

F.W.: 118.16 g/mol

pH @ 20°C: 5.0 - 7.0

COAs and Tech Docs

Guanidine Thiocyanate is a chaotropic agent. As one of the strongest protein denaturants, it inactivates nucleases more than twice as fast as Guanidine Hydrochloride. Guanidine Thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms. Higher molarity solutions of Guanidine Thiocyanate irreversibly inactivate RNase. Guanidine Thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures.


This is a non-GMP manufactured Product.


These are general specifications. BioSpectra will customize our products to meet your quality based requirements.

 

ANALYSIS SPECIFICATIONS
Appearance and Color  
White / Crystals
Assay, dried Basis  
≥ 99.0%
Enzymes

DNase

RNase
None Detected
None Detected
Heavy Metals (as Lead) ≤ 5ppm
Identification (IR)  
Conforms to Structure
Solubility (Colour)  
Colorless
Solubility (Turbidity) 100mg/mL H2O  
Clear
Trace Metals

Barium (Ba)
Iron (Fe)
Potassium (K)
Sodium (Na)
≤0.0005%
≤0.0005%
≤0.005%
≤0.5%
Printable Version
Key Compliance Attributes of Bio Ultra Grade
Suitable for Research and Diagnostic Application
C of A Available for Each Lot
Management of Change
Trace Metals Analyzed
Stability Testing Program
BioSpectra Supply Chain Audit Trail
Product Origin Statement
Customer Quality Audits
Customized Additional Specifications
Enzyme Tested
List of C of As files
GT5221-009-1120.pdf
GT5221-008-1020.pdf
GT5221-007-0920.pdf
GT5221-006-0820.pdf
GT5221-005-0820.pdf
GT5221-004-0820.pdf
GT5221-002-0620 K010.pdf
GT5221-002-0620 K001.pdf
GT5221-001-0620 K010.pdf
GT5221-001-0620 K001.pdf

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Review the below Intended End Use Statements for each Grade and Choose the Product Grade that is most applicable to your use.


a.) Bio Pharma Grade INTENDED USE: Material represented by this Grade is suitable to be used only as the following: IPEC Compliant GMP Manufactured Chemical, for use in further Manufacturing or as a Reagent for Laboratory and Research. The material represented by this Grade is not suitable to be used as an Active Pharmaceutical Ingredient, Drug, Drug Product or Household Item.


b.) Bio Excipient Grade INTENDED USE: Material represented by this Grade is suitable to be used only as the following: ICH Q7 Compliant cGMP Manufactured Excipient for use in further Manufacturing. The material represented by this Grade is not suitable to be used as an Active Pharmaceutical Ingredient, Drug Product or Household Item.


c.) O Bio Active Grade INTENDED USE: Material Represented by this Grade is suitable to be used only as the following: ICH Q7 Compliant cGMP Manufactured Active Pharmaceutical Ingredient for use in further Manufacturing or use in Drug Product Manufacturing. The material represented by this Grade is not suitable to be used as a Sterile or Injectable Active Pharmaceutical Ingredient, Drug Product or Household Item. (This statement will change depending on the status of your Drug Application in accordance with 21 CFR §201.122)

General Product Description:

• Guanidine Thiocyanate is a White/Colorless Crystalline or Powder product.
• Molecular Formula: C2H6N4S
• Molecular Weight: 118.16 g/mol.
• CAS Number: 593-84-0.
• Synonyms: Guanidine Isothiocyanate.

 



Compliance:

Material represented by this grade is suitable to be used only as the following: Quality System Manufactured Process Chemical for use in further manufacturing or as a reagent chemical for commercial manufacturing, diagnostic and laboratory research. The material represented by this grade is not suitable to be used as an Excipient, Active Pharmaceutical Ingredient, Drug, Drug Product or household item.

Expiration/Retest Date:

Two years from date of manufacture, testing and packaging.

Storage and Shipping Conditions:

Ship and Store in ambient temperature.

Package Sizes:

10kg, 25kg and 50kg pails.