Product Category

GMP Solution

GMP Manufactured Process Chemical

Guanidine HCl 6M, GMP Grade

Product Code: GHCL-4120 | Previously: GH4120

Intended For Critical Biopharma Applications

Guanidine Hydrochloride 6M solution can be used to denature proteins which become randomly coiled with no residual structure. This concentration is also used to decrease enzyme activity. The denatured proteins can be modified or analyzed using mass spectrometry, electrophoresis and enzymatic digests. As a chaotropic agent, Guanidine Hydrochloride solution is also used to break the hydrogen bonds in the structure of proteins and increase the solubility of hydrophobic molecules.

Product Specifications

Appearance and Color  
Clear, Colorless Liquid
Heavy Metals  
< 10 ppm
Identification (IR)  
Passes Test
≤ 3 ppm
5.5-6.5 M
Printable Version

Product Inquiry

Please enter your first name

Please enter title

Please enter product of interest

Enter name of company

Please enter your last name

Please enter your valid email address

Enter position in company

Location of company
Please enter street address

Enter your company state

Invalid Input

Please enter city

Enter zip code

Enter Country

Enter country code

Enter phone number

Enter web address

Please select any option

If resale please fill out the following information
Enter end use customer's full name

Enter end use customer's address

Please select any option

Please select any one option

Please select any option

Invalid Input

Please select any one option

Invalid Input

Invalid Input

Please enter Estimated Release quantity in Liters or Kg

Please enter Regulatory Requirements

Please enter timeframe needed

Please enter Estimated annual demand in liters or kg

Please enter Logistics: Freight

Please enter specificatoin

Validate Recaptcha

General Product Description:

  • The manufacturing of Guanidine Hydrochloride GHCL-4120 is performed at BioSpectra’s Stroudsburg, PA facility utilizing dedicated equipment. Equipment used in the manufacturing of GHCL-4120 is cleaned in accordance with
  • BioSpectra’s Cleaning Validation Plan.
  • Guanidine Hydrochloride 6M is a clear colorless solution.
  • There are no known major food allergens (as defined by FDA and WHO) in the manufacture of this product.
  • BioSpectra certifies that all Guanidine Hydrochloride 6M GHCL-4120 manufactured at BioSpectra and its raw materials are not derived from or come in contact with animal parts, products, and/or byproducts.
  • Guanidine Hydrochloride 6M manufactured at BioSpectra and any raw materials used in the manufacture of
  • Guanidine Hydrochloride 6M at BioSpectra are not subject to genetic modification.
  • Synonyms: Guanidine Monohydrochloride, Guanidinium Chloride, Guanidinium Hydrochloride.
  • Manufactured with USP grade purified water.

GMP Compliance:

Bio Pharma Grade Guanidine Hydrochloride 6M, GHCL-4120 is suitable for use as a process chemical. It is manufactured in accordance with the IPEC- PQG Joint Good Manufacturing Practice Guide. This grade of Guanidine Hydrochloride is not suitable to be used as an Active Pharmaceutical Ingredient, Drug, Drug Product or Household Item.

Retest Date:

The recommended retest period for Guanidine Hydrochloride 6M is two years from the date of manufacture.

Storage and Shipping Conditions:

Ship and Store in ambient temperature.

Package Sizes:

Available in 200L drums and totes.

Additional Packaging Information