MOPS, Free Acid - GMP Buffer

BIO PHARMA GRADE | MP4220 | CAS#: 1132-61-2

INTENDED FOR USE IN PHARMACEUTICAL GMP PROCESSES

Product-image
formula-image

BIO PHARMA GRADE / MP4220

CAS #: 1132-61-2

Molecular Formula:

C7H15NO4S

Solubility in Water (g/L): 980

F.W.: 209.26 g/mol

pH @ 20°C: 3.0 - 4.5

Useful pH: 6.5 - 7.9

pKa @ 20˚C: 7.2

MOPS is a zwitterionic buffer used as a running buffer for denaturing gel electrophoresis and as a buffering agent in many biological and biochemical applications. MOPS interferes with the Folin protein assay and partially decomposes when autoclaved in the presence of glucose. MOPS can be used as a Good’s buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.


These are general specifications. BioSpectra will customize our products to meet your quality based requirements.

ANALYSIS SPECIFICATIONS
  250 nm
Absorbance (0.1M) 260 nm
  280 nm
0.020 a.u. maximum
0.020 a.u. maximum.
0.020 a.u. maximum
Appearance and Color  
White / Crystals
Assay  
99.5% min.
Chloride  
0.005% max.
Enzymes

DNase

RNase

Protease

None Detected
None Detected
None Detected
Identification (IR)  
Passes Test
Karl Fischer Water  
0.1% max.
Loss on Drying  
1.0% max.
pH (1% solution)  
3.0-4.5

pH (2.5M)

 
2.5-4.5
pKa  

7.0-7.5

Residue on Ignition  
0.1% max.
Solubility (5%)  
Passes Test
Sulfate  
0.005% max.
Trace Metals Arsenic (As)
Copper (Cu)
Iron (Fe)
Lead (Pb)
5 ppm max.
5 ppm max.
5 ppm max.
5 ppm max.
Printable Version
Key Compliance Attributes of BioSpectra Grades Bio Pharma Grade IPEC GMP Compliant Manufactured
Suitable for Research and Diagnostic  
Yes
Each Batch 100% Analyzed  
Yes
Management of Change  
Yes
Validated Analytical Methods  
Yes
Compendial Testing  
Yes
Trace Metals Analyzed  
Yes
Two Year Stability  
Yes
BioSpectra Supply Chain Audit Trail  
Yes
Product Origin Statement  
Yes
Customer Quality Audits  
Yes
Customized Additional Specifications  
Yes
Multi-Compendial Testing  
Yes
Enzyme Tested  
Yes
Validated Manufacturing Process  
Yes
US Manufactured at BioSpectra  
Yes
IPEC cGMP Compliant Manufactured  
Yes
Suitable for use as Excipient  
Available
Microbial / Endotoxin Tested  
Available
Manufactured in FDA Registered Facility  
Available
Customized Manufacturing Schedule  
Available
Custom Regulatory Packet  
Available
Accelerated Stability  
Available

Product Inquiry

Please enter your first name

Please enter title

Please enter product of interest

Enter name of company

Please enter your last name

Please enter your valid email address

Enter position in company

Location of company
Please enter street address

Enter your company state

Invalid Input

Please enter city

Enter zip code

Enter Country

Enter country code

Enter phone number

Enter web address

Please select any option

Please identify end use customer by full name and address
Enter end use customer's full name

Enter end use customer's address

Please select any option

Please select any one option

Please select any option

Invalid Input

Please select any one option

Invalid Input

Invalid Input

Please enter Estimated Release quantity in Liters or Kg

Please enter Regulatory Requirements

Please enter timeframe needed

Please enter Estimated annual demand in liters or kg

Please enter Logistics: Freight

Please enter specificatoin

Validate Recaptcha

Review the below Intended End Use Statements for each Grade and Choose the Product Grade that is most applicable to your use.


a.) Bio Pharma Grade INTENDED USE: Material represented by this Grade is suitable to be used only as the following: IPEC Compliant GMP Manufactured Chemical, for use in further Manufacturing or as a Reagent for Laboratory and Research. The material represented by this Grade is not suitable to be used as an Active Pharmaceutical Ingredient, Drug, Drug Product or Household Item.


b.) Bio Excipient Grade INTENDED USE: Material represented by this Grade is suitable to be used only as the following: ICH Q7 Compliant cGMP Manufactured Excipient for use in further Manufacturing. The material represented by this Grade is not suitable to be used as an Active Pharmaceutical Ingredient, Drug Product or Household Item.


c.) O Bio Active Grade INTENDED USE: Material Represented by this Grade is suitable to be used only as the following: ICH Q7 Compliant cGMP Manufactured Active Pharmaceutical Ingredient for use in further Manufacturing or use in Drug Product Manufacturing. The material represented by this Grade is not suitable to be used as a Sterile or Injectable Active Pharmaceutical Ingredient, Drug Product or Household Item. (This statement will change depending on the status of your Drug Application in accordance with 21 CFR §201.122)

General Product Description:

  • The manufacturing of Bio Pharma Grade MOPS MP4220 is performed at BioSpectra’s Stroudsburg, PA facility and is conducted in a dedicated processing area using only dedicated equipment.
  • MOPS is a White Crystalline product.
  • Molecular Formula: C7H15NO4S
  • Molecular Weight: 209.26 g/mol.
  • CAS Number: 1132-61-2.
  • There are no known major food allergens (as defined by FDA and WHO) in the manufacture of this product.
  • BioSpectra certifies that all MOPS MP4220 manufactured at BioSpectra and its raw materials are not derived from or come in contact with animal parts, products, and/or byproducts.
  • MOPS manufactured at BioSpectra and any raw materials used in the manufacture of MOPS at BioSpectra are not subject to genetic modification.
  • Synonyms: 3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid.


GMP Compliance:

Bio Pharma Grade MOPS MP4220 is manufactured in accordance
with cGMP guidelines and is suitable to be used only as the
following: IPEC Compliant GMP Manufactured Chemical, for
use in further Manufacturing or as a Reagent for Laboratory
and Research. This Grade of MOPS is not suitable to be used
as an Active Pharmaceutical Ingredient, Drug, Drug Product or
household item.

Expiration/Retest Date:

The recommended retest period for MOPS is two years from the
date of manufacture.

Storage and Shipping Conditions:

Ship and Store in ambient temperature.

Package Sizes:

10kg, 25kg and 50kg pails.