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Reagent

TRIS (TROMETHAMINE)

Product Code: TRIS-5220

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QUANTITY
Product Code: TRIS-5220 | Previously: TR5220
INTENDED FOR USE IN COMMERCIAL MANUFACTURING, DIAGNOSTIC AND LABORATORY APPLICATIONS

Tris, commonly used as a buffer in biochemistry and molecular biology, stabilizes the pH of solutions in electrophoresis and other biological applications. It is also an enzyme inhibitor used in the biopharmaceutical industry and is commonly utilized in electro-chromatography, UV analysis and HPLC applications. Tris is extensively used as a biological buffer or a component of buffer solutions. Tris can be used as a Good’s buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.

CAS #: 77-86-1
Molecular Formula: C4H11NO3
Solubility in Water (g/L): 550
F.W.: 121.14 g/mol
pH @ 20°C: 10.0 - 11.5
Useful pH: 7.0 - 9.0
pKa @ 20˚C: 8.3

Product Specifications

ANALYSIS SPECIFICATIONS
Absorbance (40%) 290 nm
0.02 a.u. max.
Appearance and Color  
White / Crystals
Assay  
99.8-100.1%
Heavy Metals  
5 ppm max
Identification B  
Passes Test
Identification C  
Passes Test
Identification (IR)  
Passes Test
Insoluble Matter  
0.005% maximum
Karl Fischer Water  
2% maximum
Loss on Drying  
1% maximum
Melting Range  
168–172˚C

pH

 
10.0–11.5
Residue On Ignition  
0.1% maximum
Trace Metals Iron (Fe)
5 ppm maximum
Printable Version

General Product Description:

  • Tromethamine is a White Crystalline product
  • Molecular Formula: C4H11NO3
  • Molecular Weight: 121.14 g/mol.
  • CAS Number: 77-86-1.
  • Synonyms: Tris, Tromethamine, Tris (hydroxymethyl) aminomethane.

Intended Use Statement::

Material represented by this grade is suitable to be used only as the following: Quality System Manufactured Process Chemical for use in further manufacturing or as a reagent for laboratory and research. The material represented by this grade is not suitable to be used as an Excipient, Active Pharmaceutical Ingredient, Drug, Drug Product or household item.

Retest Date:

BioSpectra does not assign expiration or retest dates for Bio Ultra Grade materials.

Storage and Shipping Conditions::

Ship and Store in ambient temperature

Package Sizes:

10kg, 25kg and 50kg pails.

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.