Tris / Tromethamine USP, EP, ACS, LBLE

BioBuffer Solution Brand Product - TEMPORARILY UNAVAILABLE, Please Inquire for Lead Time.

Process Chemical

ISO Certified

Tris / Tromethamine

USP, EP, ACS, LBLE*

Product Code: TRIS-6250

*Low Bioburden and Low Endotoxin

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Product Code: TRIS-6250

Suitable for use in biological and biotech chemical process applications from R&D through scale production.

Tris / Tromethamine is commonly used as a buffer and excipient in downstream biological applications during the manufacture of drug products. Tris is considered a Good's buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.

CAS #: 77-86-1
Formula: NH₂C(CH₂OH)₃
F.W.: 121.14 g/mol

Product Specifications

Analysis

Specifications

Absorbance (10%)

260 nm

280 nm

430 nm

< = 0.03 a.u.

< = 0.02 a.u.

< = 0.004 a.u.

Absorbance (40%)

280 nm

290 nm

400 nm

430 nm

< = 0.06 a.u.

< = 0.20 a.u.

< = 0.02 a.u.

< = 0.03 a .u.

APHA Color, 20% Aqueous Solution

< = 20 APHA

Appearance (EP)

Clear and Colorless

Assay, Dried Basis (USP/EP)

> = 99.9 - 100.1%

Chloride (EP)

< = 100 ppm

Elemental Impurities

< = 2000

Endotoxin

< = 2.5 EU/g

Heavy Metals

< = 5 ppm

Identification A (EP, pH 5%) (USP)

Passes Test

Identification B (USP), Melting Range (EP)

168 - 172°C

Identification C (USP/EP)

Passes Test

Insoluble Matter

< = 0.005%

Loss on Drying (EP)

< = 0.5%

Related Substances

< = 1.0%

Residual Solvents (USP)

Passes Test

Residue on Ignition (USP) / Sulfated Ash (EP)

< = 0.1%

Microbial Content

TAMC
TYMC

< = 10 CFU/g
< = 10 CFU/g

Sulfate

< = 5 ppm

Trace Metals

Aluminum (Al)

Arsenic (As)

Barium (Ba)

Cadmium (Cd)

Calcium (Ca)

Chloride (Cl)

Chromium (Cr)

Cobalt (Co)

Copper (Cu)

Iron (Fe)

Lead (Pb)

Lithium (Li)

Magnesium (Mg)

Manganese (Mn)

Nickel (Ni)

Potassium (K)

Sodium (Na)

Strontium (Sr)

Zinc (Zn)

< = 5 ppm

< = 1 ppm

< = 5 ppm

< = 10 ppm

< = 2 ppm

< = 5 ppm

< = 2 ppm

< = 1 ppm

< = 5 ppm

< = 1 ppm

< = 50 ppm

< = 5 ppm

Water

< = 0.2%

Key Product Features:

Appears as a white, crystalline powder
Manufactured in accordance with the ISO Certified Quality Management System
Manufactured in an enzyme free, hormone free and animal free environment
Contains no major food allergens (as defined by FDA and WHO)
The final product and its raw materials are not derived from nor come into contact with animal parts, animal products, and/or animal byproducts or derivatives.
Is not subject to genetic modification
Synonyms: Trometamol; THAM; Tris (Hydroxyethyl) Aminomethane; Trisaminol; Trismethylolaminomethane; 2-Amino-2(Hydroxymethyl) propane-1,2-diol

Shelf-Life Policy:

Please inquire for information regarding shelf life.

Storage & Shipping:

Refer to SDS.

Package Sizes:

1kg, 5kg, 10kg, 25kg, and 50kg

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.