GUANIDINE HCl

MOLECULAR BIOLOGY GRADE, Ultrapure / GH5222

INTENDED FOR USE IN DIAGOSTIC AND LABORATORY APPLICATIONS

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MOLECULAR BIOLOGY GRADE, ultrapure / GH5222

CAS #: 50-01-1

Molecular Formula:

CH5N3 • HCl

Solubility in Water (g/L): 800

F.W.: 95.53 g/mol

pH @ 20°C: 4.5 - 6.0

COAs and Tech Docs

Guanidine Hydrochloride is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. As a chaotropic agent, it breaks down the structure of proteins. Guanidine Hydrochloride is commonly used in the purification of RNA by dissociating the RNA into its nucleic acids and protein forms. At higher concentrations, Guanidine Hydrochloride decreases enzyme activity. It is also used to increase the solubility of hydrophobic molecules.

These are general specifications. BioSpectra will customize our products to meet your quality based requirements.

ANALYSIS SPECIFICATIONS
Appearance  
Colourless Crystals
Solubility(6M, 50% w/w, in water)  
Clear, colorless
Assay  
99.7% min.
Melting Point  
185-188°C
Water  
0.1% max.
Iron  
0.1 mg/kg max.
Heavy Metals (Pb)  
10 mg/kg max.
pH (6M, 50% w/w, in water)  
4.5 – 7.0
UV-Absorbance (6M, 50% in water)

@ 280 nm

@ 260 nm

@ 240 nm

@ 230 nm

Informative

0.03 a.u. max.

Informative

Informative

Ammonium  
0.01% max.
Dicyandiamide  
0.01% max.
Melamine  
0.01% max.
Enzymes(0.1M aq.sol.)

Protease

Phosphatase

DNAse

RNAse

Informative

Informative

Informative

Informative

Printable Version
Key Compliance Attributes of Bio Ultra Grade
Suitable for Research and Diagnostic Application
C of A Available for Each Lot
Management of Change
Trace Metals Analyzed
Stability Testing Program
BioSpectra Supply Chain Audit Trail
Product Origin Statement
Customer Quality Audits
Customized Additional Specifications
Enzyme Tested
List of C of As files
No files available right now.

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General Product Description:

• Guanidine HCl is a White Crystalline product.
• Molecular Formula: NH 2 C(NH)NH 2 HCl
• Molecular Weight: 95.53 g/mol.
• CAS Number: 50-01-1.
Synonyms: Guanidine Monohydrochloride,
Guanidinium Chloride, Guanidinium Hydrochloride.



Compliance:

Material represented by this grade is suitable for use as a process chemical. This grade of Guanidine Hydrochloride is not suitable to be used as an Excipient, Active Pharmaceutical Ingredient, Drug, Drug Product or Household Item.

Expiration/Retest Date:

Two years from the date of manufacture, testing and packaging.

Storage and Shipping Conditions:

Ship and Store in ambient temperature.

Package Sizes:

10 kg, 25 kg and 50 kg pails.