Guanidine Hydrochloride, CAS# 50-01-1

Guanidine Hydrochloride

Molecular Fomula: NH₂C(NH)NH₂ HCl
F.W.: 95.53
CAS#: 50-01-1
pH @ 20° C: 4.5 - 6.0
Solubility in water (g/ml): 2.15


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Description:
Guanidine HCl is a chaotropic agent used to disrupt the structure of proteins. As a denaturant it acts to unfold proteins and turn them into their original polypeptide chains. It is commonly utilized in the isolation of RNA by dissociating the RNA into its nucleic acids and protein forms. At higher concentrations Guanidine HCl decreases enzyme activity. It is also used to increase the solubility of hydrophobic molecules.

Specifications Product Links

Guanidine Hydrochloride

NH₂C(NH)NH₂^.HCl ^ F.W. 95.53 g/mol ^ CAS# 50-01-1

ANALYSIS		SPECIFICATIONS

		Bio Ultra GHL-13	Bio Synthesized GHL-12	Bio Reagent GHL-11

Absorbance	@ 275	0.030 a.u. max.	0.050 a.u. max.
	@ 260	0.030 a.u. max.	0.050 a.u. max.
	@ 230	0.200 a.u. max.	0.300 a.u, max.
Appearance and Color		White/Crystals	White/Crystals	White to Off-White/Crystals
Assay		99.5% min.	99.0% min.	98.0% min.
Identification (IR)		Passes Test	Passes Test	Passes Test
Insoluble Matter		0.15% max.
Loss on Drying		0.5% max.
Melt Range °C		184°C -188°C	184°C - 188°C
Nitrate		0.01%
pH		4.5 - 6.0	4.5-6.0
Residue on Ignition		0.05% max.	0.05% max.
Solubility (6M)		Passes Test	Passes Test
Sulfate		0.01% max.
Trace Metals	Arsenic (As)	0.0005% max.
	Copper (Cu)	0.0005% max.
	Iron (Fe)	0.0005% max.
	Lead (Pb)	0.0005% max.
Enzymes	RNase	None Detected
	DNase	None Detected
	Protease	None Detected

Guanidine Hydrochloride MSDS (CAS# 50-01-1)

Guanidine Hydrochloride Inhibits Mammalian Orthoreoviris Growth by Reversibly Blocking the Synthesis of Double-Stranded RNA

EnvironmentalChemistry.com chemical Database

Unfolding and Inactivation of Abalone (Haliotis diversicolor) Alkaline Phosphatase During Denaturation by guanidine Hydrochloride

Drug Card for Guanidine

Product	Molecular	CAS #	Details
Guanidine Thiocyanate	NH₂C(NH)NH₂ HSCN	593-84-0
Guanidine Thiocyanate	NH₂C(NH)NH₂ HSCN	593-84-0
Tris Hydrochloride	C₄H₁₁NO₃ClH	1185-53-1

Bio Reagent (Good)
Quality tested from approved suppliers of BBS for Industry-Standard use.

Bio Synthesized (Better)
Manufactured in a quality system based facility offering traceability and consistent supply.

Bio Ultra (Best)
Manufactured at BBS to meet the highest quality and regulatory standards.